Cartilage canals in sharks and rays show that blood vessels can exist in mature cartilage without triggering endochondral bone formation
Benjamin Flaum, Ronald Seidel, Maxi Yeatman-Biggs, Theda I. Hinrichs, Jana Ciecierska‐Holmes, Salman O. Matan, Emilio J. Gualda, Kady Lyons, Victoria Camilieri‐Asch, Sue R. McGlashan, Laura J. Ekstrom, Lawrence J. Bonassar, Mélanie Debiais‐Thibaud, Daniel Baum, Michael J.F. Blumer, Mason N. Dean
This study shows that sharks and rays have cartilage canals in their adult skeletons, which are vascular but do not trigger endochondral bone formation, suggesting an ancient role in nutrient transport.
iScience · Oct 31, 2026Peer-reviewedEvolutionary Biology