Lawrence J. Bonassar

This study shows that sharks and rays have cartilage canals in their adult skeletons, which are vascular but do not trigger endochondral bone formation, suggesting an ancient role in nutrient transport.

This study investigates shear strain stiffening in cartilage, showing it results from a mechanical phase transition between bending- and stretching-dominated modes, influenced by collagen concentration and compression.

This study compares the ability of collagen type II and I to form synovial fluid films and retain lubricin, revealing differences in their functional roles in joint mechanics.

This study shows that a single delayed injection of recombinant human lubricin improves cartilage repair tissue quality and lubrication in a rabbit osteochondral defect model.

This study uses 3D tomography to show collagen scaffolds exhibit auxetic behavior due to instability under compression, which affects their performance in tissue engineering.

This study develops recombinant lubricin analogs with improved biocompatibility and lubricating properties, demonstrating their tissue binding and joint retention in rats.