Seaweed-derived Bioactive Compounds

Untargeted metabolomics reveals a selectively enriched surface metabolome underpinning constitutive chemical defence in the red alga Halymenia floresii (Clemente) C.Agardh, 1817 ((Rhodophyta, Halymeniales)

This study uses untargeted metabolomics to show that the red alga Halymenia floresii selectively enriches lipid-associated metabolites at its surface for chemical defense against microbial colonization.

Fermentation of the Edible Brown Seaweed Alaria esculenta by Lactiplantibacillus plantarum affects nutritional prfile and the content of potentially toxic elements.

This study investigates how Lactiplantibacillus plantarum fermentation alters the nutritional profile and toxic element content of Alaria esculenta.

Species-dependent antifungal profiles reveal stronger yeast inhibition by chitosan than by a sulfate-containing polysaccharide-rich extract from Jania adhaerens

This study compares the antifungal activity of chitosan and a sulfate-containing polysaccharide extract from Jania adhaerens against various yeast species, finding chitosan generally more effective but with species-specific resistance.

Low-molecular-weight Ulva lacinulata extract exhibiting anti-inflammatory and pro-autophagic activities in RAW 264.7 macrophages: a promising candidate for the development of active ingredients targeting low-grade inflammation

This study evaluates a marine extract from Ulva lacinulata, showing it reduces pro-inflammatory cytokines and activates autophagy in macrophages, suggesting potential as a functional ingredient for inflammation management.

Fucoidan from brown algae Laminaria japonica trigger apoptosis in colon cancer cells

This study shows that fucoidan from Laminaria japonica induces apoptosis in colon cancer cells via the mitochondrial intrinsic pathway, without involving necroptosis.

Crude Fucus vesiculosus fucoidan demonstrates superior SARS-CoV-2 antiviral activity compared to its pure form: binding kinetics and functional studies

This study compares the antiviral activity of crude and pure fucoidan against SARS-CoV-2, finding that crude fucoidan has higher binding affinity and inhibitory potency.

Phytochemical profiling and antioxidant potential of freshwater algal extracts from Lahore, Pakistan, with preliminary evaluation of cytotoxic activity

This study evaluates the phytochemical composition, antioxidant activity, and cytotoxic potential of freshwater algal extracts from Lahore, Pakistan, identifying n-hexane fractions as more antioxidant and ethanolic extracts as moderately cytotoxic.

Screening antifungal activity of macroalgae from SE Spain highlights the invader Rugulopteryx okamurae

This study evaluates the antioxidant and antifungal activities of extracts from invasive and native macroalgae in SE Spain, finding R. okamurae has strong antifungal activity against Fusarium oxysporum TR4.

Fucoidan exerts anti-cancer activity in a 3D prostate spheroid cell culture model.

This study evaluates fucoidan's effects on prostate cancer spheroids, showing dose-dependent viability and migration changes, and gene expression differences in PC-3 and LNCaP cells.

Biofortification of green seaweed Ulva with Vitamin B12 using Lacticaseibacillus rhamnosus and Lactococcus lactis

This study biofortifies green seaweed Ulva with Vitamin B12 using bacterial fermentation, achieving 19.6 g/mL of Vitamin B12 after 72 hours.

In vitro and in vivo evaluation of Ulva lactuca for wound healing

This study evaluates ethanol and aqueous extracts of Ulva lactuca for their antioxidant, anti-inflammatory, and wound healing properties in vitro and in vivo.