Laser Applications in Dentistry and Medicine

Dose dependence and neurovascular mechanisms of the fMRI response to pulsed photobiomodulation in humans

This study investigates the dose-dependent fMRI response to transcranial photobiomodulation in humans, showing non-local effects and parameter-dependent responses.

Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation

This study shows red light stimulates mitochondrial fatty acid oxidation in keratinocytes via AMPK activation, unlike UV or blue/green light which cause toxicity or metabolic disruption.

Evaluation of near-infrared light therapy for the treatment of neurodegenerative diseases: Limited penetration depth into the brain likely hinders efficacy

This study evaluates the effectiveness of near-infrared light therapy for neurodegenerative diseases by measuring light penetration through human skulls and its biological effects on neurons and C. elegans.

Transcranial photobiomodulation enhances visual working memory capacity in humans

This study shows that 1064 nm transcranial photobiomodulation on the right prefrontal cortex improves visual working memory capacity and related neural activity in humans.

Red-light (670 nm) therapy reduces mechanical sensitivity and neuronal cell death, and alters glial responses following spinal cord injury in rats

Near-infrared light increases functional connectivity with a non-thermal mechanism

This study shows near-infrared light increases brain functional connectivity without causing thermal changes, suggesting a non-thermal mechanism for transcranial photobiomodulation.