Topic · Surgery · Medicine

Anorectal Disease Treatments and Outcomes

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Research Letter: Therapeutic targets for haemorrhoidal disease: proteome-wide Mendelian randomisation and colocalization analyses

This study identifies 5 causal plasma proteins associated with haemorrhoidal disease using Mendelian randomisation and colocalization analyses, with ERLEC1 showing differential expression in tissue.

Gut · Feb 5, 2024Peer-reviewedGenetic & Genomic Medicine

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

Tenghao Zheng, David Ellinghaus, Simonas Juzėnas, François Cossais, Greta Burmeister, Gabriele Mayr B, Isabella Friis Jørgensen, Maris Teder‐Laving, Anne Heidi Skogholt, Sisi Chen, Peter R. Strege, Go Ito, Karina Banasik, Thomas Becker, Frank Bokelmann, , André Franke

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.

Gut · Apr 22, 2021Peer-reviewedGenetic & Genomic Medicine