Author

Thomas Becker

University of Edinburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1

Frequent Co-Authors

Catherina Gwynne BeckeriD· 3 shared Leonardo Cavone· 2 shared Alberto Docampo-SearaiD· 1 shared Alexander HendricksiD· 1 shared André FrankeiD· 1 shared Andrea GsuriD· 1 shared Anita PanditiD· 1 shared Anja Bretschneider· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersNeuroscience

Catherina Gwynne BeckerORCID

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Author profile →

4 papers

Recent·Most cited

A reparative neutrophil subpopulation promotes spinal cord regeneration in zebrafish by controlling macrophage inflammation via Il-4

Xiaobo Tian, Alberto Docampo-Seara, Kim Heilemann, Friederike Kessel, Daniela Zöller, Anja Bretschneider, Thomas Becker, Catherina Gwynne Becker

The paper shows that a neutrophil subpopulation expressing il4 promotes spinal cord regeneration in zebrafish by reducing Il-1β in macrophages/microglia, and this effect can be rescued by il4 overexpression or Il-1β reduction.

bioRxiv · Feb 26, 2026 · PreprintNeuroscience

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

Tenghao Zheng, David Ellinghaus, Simonas Juzėnas, François Cossais, Greta Burmeister, Gabriele Mayr B, Isabella Friis Jørgensen, Maris Teder‐Laving, Anne Heidi Skogholt, Sisi Chen, Peter R. Strege, Go Ito, Karina Banasik, Thomas Becker, Frank Bokelmann, , André Franke

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.

Gut · Apr 22, 2021Peer-reviewedGenetic & Genomic Medicine

Regeneration of dopaminergic neurons in adult zebrafish depends on immune system activation and differs for distinct populations.

Lindsey J. Caldwell, Nick O. Davies, Leonardo Cavone, Karolina Sandra Mysiak, Svetlana A. Semenova, Pertti Panula, J. Douglas Armstrong, Catherina Gwynne Becker, Thomas Becker

The paper shows that adult zebrafish regenerate dopaminergic neurons, but this capacity varies between populations and depends on immune system activation.

Journal of Neuroscience · Apr 4, 2019Peer-reviewedNeuroscience

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, Tahimina Munir, Marcus Keatinge, Marvin Lambertus, Anna Underhill, Thomas Barrett, Elias Kassapis, Nikolay V. Ogryzko, Yi Feng, Tjakko J. van Ham, Thomas Becker, Catherina Gwynne Becker

The paper shows that macrophage-mediated dynamic control of Il-1β and Tnf-α is essential for spinal cord regeneration in zebrafish.

Nature Communications · Nov 1, 2018Peer-reviewedDevelopmental Biology