Topic · Physiology · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
32 papers
Farr Niere, Luisa P. Cacheaux, Hailey X. Egido‐Betancourt, William C. Taylor, Kimberly F. Raab‐Graham
The paper identifies Bay-K8644 as a potential therapy for TS-related seizures by boosting L-type Ca2+ channel activity and reducing excess GluA receptors in a mouse model.
bioRxiv · Aug 26, 2020 · PreprintNeuroscience
Polina Kosillo, Natalie M. Doig, Kamran M. Ahmed, Alexander H.C.W. Agopyan-Miu, Corinna D. Wong, Lisa Conyers, Sarah Threlfell, Peter J. Magill, Helen S. Bateup
This study shows that loss of Tsc1 in midbrain dopamine neurons leads to structural and functional defects, causing cognitive flexibility deficits that can be mitigated by reducing Raptor.
Nature Communications · Nov 28, 2019Peer-reviewedNeuroscience