Author

William C. Taylor

Wake Forest University Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Farr NiereiD· 2 shared Hailey X. Egido‐BetancourtiD· 2 shared Kimberly F. Raab‐GrahamiD· 2 shared Luisa P. CacheauxiD· 2 shared Ayse UneriiD· 1 shared Cameron Reynoldson· 1 shared Christopher Dirk KeeneiD· 1 shared Colin J. McArdle· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Farr NiereORCID

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Author profile →

2 papers

Recent·Most cited

Boosting L-type Ca2+ channel activity in tuberous sclerosis mitigates excess glutamate receptors

Farr Niere, Luisa P. Cacheaux, Hailey X. Egido‐Betancourt, William C. Taylor, Kimberly F. Raab‐Graham

The paper identifies Bay-K8644 as a potential therapy for TS-related seizures by boosting L-type Ca2+ channel activity and reducing excess GluA receptors in a mouse model.

bioRxiv · Aug 26, 2020 · PreprintNeuroscience

Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer's disease

Farr Niere, Ayse Uneri, Colin J. McArdle, Luisa P. Cacheaux, Hailey X. Egido‐Betancourt, Sanjeev V. Namjoshi, Cameron Reynoldson, Juan Penaranda, Xin Wang, William C. Taylor, Suzanne Craft, Christopher Dirk Keene, Tao Ma, Kimberly F. Raab‐Graham

The paper identifies a novel DJ-1/2δ2/L-VDCC pathway disrupted in tuberous sclerosis and Alzheimer's disease, linking mTORC1 signaling to L-type calcium channel hypoactivity.

bioRxiv · Aug 26, 2020 · PreprintNeuroscience