Topic · Ophthalmology · Medicine

Retinal and Optic Conditions

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Dissecting the ocular impact of SARS-CoV-2 variants: Analysis of eye globe and retina in animal models

Julianna Lopes da Silva, Victor Kersten, Lívia Mendonça Munhoz Dati, Bruna Bezerra Lins, Tania R. Tozzeto-Mendoza, Daniela del Rosário Flores Rodrigues, Rodrigo Jorge Vianna-Barbosa, Silvia Helena Lima, Lucy Santos Villas Boas, Alexandre dos Santos da Silva, Khallil Taverna Chaim, Maria Cássia Mendes-Corrêa, Momtchilo Russo, Luciana Cristina Mirotti, Marcelo Alves Pinto, Rodrigo A. P. Martins

This study examines the effects of SARS-CoV-2 variants on the eye and retina in animal models, finding limited impact with no inflammation observed in hamster retinas.

bioRxiv · May 29, 2024 · PreprintNeuroscience

SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids

Yotam Menuchin-Lasowski, André Schreiber, Aarón Lecanda, Angeles Mecate‐Zambrano, Linda Brunotte, Olympia Ekaterini Psathaki, Stephan Ludwig, Thomas Rauen, Hans Robert Schöler

This study shows SARS-CoV-2 can infect and replicate in retinal organoids, affecting photoreceptor and retinal ganglion cells, and induces inflammatory gene expression.

Stem Cell Reports · Mar 24, 2022Peer-reviewedMolecular Biology