Olympia Ekaterini Psathaki

Multi-scale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts

This study investigates age-related mitochondrial cristae structural changes in human and mouse hearts, linking Opa1 downregulation to reduced OXPHOS capacity without affecting core subunit levels.

Localisation of Apicomplexa motor Myosin A with axial nanometric precision using graphene energy transfer

This study localizes Myosin A in Toxoplasma gondii with 1-4 nm axial precision using graphene energy transfer, supporting the linear migration motor model.

Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites

This study shows that Pex3 promotes peroxisome-peroxisome and peroxisome-lipid droplet contact sites in yeast and flies, independent of other known Pex3 partners.

Rapid in-EPON CLEM for everyone: Combining fast and efficient labeling of self-labeling enzyme tags with EM resistant Janelia Fluor dyes

The paper compares Janelia Fluor dyes and TMR for fluorescence preservation in EM-compatible in-resin CLEM, identifying JFX549 and JFX554 as optimal for signal intensity and background ratio.

A mesh microelectrode array for non-invasive electrophysiology within neural organoids

This paper introduces a mesh microelectrode array for non-invasive electrophysiology in neural organoids, demonstrating long-term culture and electrical activity recordings.

SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids

This study shows SARS-CoV-2 can infect and replicate in retinal organoids, affecting photoreceptor and retinal ganglion cells, and induces inflammatory gene expression.

Ischemic tolerance and cardiac repair in the African spiny mouse

This study demonstrates that African spiny mice exhibit improved cardiac repair and tolerance to myocardial infarction compared to other mammals.

An integrated genome-wide multi-omics analysis of gene expression dynamics in the preimplantation mouse embryo

The paper integrates multi-omics data to analyze gene expression dynamics in mouse embryos, revealing discrepancies between transcript and protein levels during early development.