Nigella sativa pharmacological applications

Evaluation of the Anti-Inflammatory and Wound-Healing Potentials of Nigella sativa Extract in Dermal Injury Models

This study evaluates Nigella sativa extract's anti-inflammatory and wound-healing effects in rat dermal injury models, showing accelerated healing and improved oxidative balance and gene expression.

Less is more: Hormetic and selective antimicrobial activity of a thymoquinone-standardized black seed oil ThymoQuin in gut microbiota models

This study evaluates the antimicrobial activity of ThymoQuin, finding it selectively modulates gut microbiota at intermediate concentrations but shows broader effects at higher doses.

Thymoquinone Inhibits BTK Expression and Phosphorylation in B-Cell Lymphoma: A Novel Plant-Derived Therapeutic Approach

This study shows thymoquinone inhibits BTK expression and phosphorylation in B-cell lymphoma cells, comparable to ibrutinib, suggesting it as a potential plant-derived therapeutic.

Anti-proliferative and Apoptosis Inducing Effect of Thymoquinone in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells

This study evaluates thymoquinone's anti-proliferative and pro-apoptotic effects on NTERA-2 cancer stem-like cells and PBMCs, showing dose- and time-dependent inhibition of proliferation and increased apoptosis.

Neuroprotective Effects of Nigella sativa Extract in a Rat model of Propionic Acid-Induced Autism Spectrum Disorder

This study evaluates the neuroprotective effects of Nigella sativa extract in a rat model of ASD induced by propionic acid, showing improvements in behavior and biochemical markers.