Synthesis and Characterization of Heterocyclic Compounds

Synthesis and In Vitro Assessment of Triazole-Based Compounds as Potential Inhibitors of Herpes Simplex Virus Type 1

This study synthesizes and evaluates triazole-pyrazine derivatives for anti-HSV-1 and antioxidant activity, finding compounds 5f and 5t show improved antiviral efficacy compared to Acyclovir.

1,2,4-Triazole-based first-in-class non-nucleoside inhibitors of bacterial enzyme MraY

This paper discovers first-in-class 1,2,4-triazole-based non-nucleoside inhibitors of MraY with broad-spectrum antibacterial activity against multiple bacterial species.