Topic · Oncology · Medicine

Ear and Head Tumors

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Disrupted astrocyte-endothelial crosstalk drives hemangioblastoma lesions in VHL disease

Macarena De Andrés-Laguillo, Irene García-Gónzalez, Susana F. Rocha, Aroa Garcia-Cabero, Sandra Ruiz-Garcia, Luis Diago-Domingo, Aimane Danana, Lorena Cussó, Katrien De Bock, José Antonio Enrı́quez, Rui Benedito

This study shows that loss of Vhl in astrocytes disrupts astrocyte-endothelial crosstalk, leading to hemangioblastoma formation in VHL disease.

bioRxiv · Sep 15, 2025 · PreprintCancer Biology

Intra-familial phenotypic heterogeneity and telomere abnormality in von Hippel-Lindau disease

Jiangyi Wang, Xiang Peng, Cen Chen, Xianghui Ning, Shuanghe Peng, Teng Li, Shengjie Liu, Baoan Hong, Jingcheng Zhou, Kaifang Ma, Lin Cai, Kan Gong

This study investigates phenotypic heterogeneity and telomere abnormalities in VHL families, finding earlier onset in children and telomere shortening linked to genetic anticipation.

Frontiers in Genetics · Apr 24, 2019Peer-reviewedGenetics