363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Neil M Davies, Matt Dickson, George Davey Smith…·Frank Windmeijer
This study uses a natural experiment to estimate the causal effects of education on health, mortality, cognition, well-being, and income using UK Biobank data.
Brian G. Williams, Somya Gupta, Matthew Wollmers, Reuben Granich
This paper models HIV and TB trends in South Africa under two scenarios, finding that expanded treatment and prevention can end AIDS by 2030.
Ethan O. Romero-Severson, Ingo Bulla, Nick Hengartner…·Thomas Leitner
This study uses approximate Bayesian computation to infer HIV-1 transmission direction, diversity, and frequency, finding that a single transmission model better explains the data than ongoing transmission.
This paper applies a Bayesian framework to analyze infection biomarkers in HIV patients with pneumonia, identifying CRP, PCT, and lytA as significant predictors and demonstrating the value of continuous likelihood ratios over dichotomous cutoffs.
This study analyzes the survival of NIH-owned chimpanzees, finding no significant association between location or recent transfers and premature mortality.
Qian Zhang, Kaiyuan Sun, Matteo Chinazzi…·Alessandro Vespignani
This paper projects the spread of Zika virus in the Americas using a data-driven stochastic model, estimating introduction timing and infection patterns.
Joseph T. Wu, Corey M. Peak, Gabriel M. Leung, Marc Lipsitch
This study models the effectiveness of fractional-dose yellow fever vaccination in reducing infection attack rate, finding it effective if vaccine efficacy exceeds 20%.
Colin J Worby, Jacco Wallinga, Marc Lipsitch, Edward Goldstein
This study simulates the impact of influenza vaccination on co-circulating vaccine-type and variant strains, showing that a bivalent vaccine reduces overall infection incidence more effectively than a monovalent vaccine.
This study quantifies and compares ZIKV and DENV antibody titers in CSF and serum of neonates with microcephaly, finding higher and persistent ZIKV titers in CSF compared to serum.
James M Wilson, Walter Brediger, Tom Albright, Julie Smith-Gagen
This study reanalyzes historical anthrax epidemic data from Rhodesia, estimating a large geographic scope and suggesting multiple independent geotemporal foci rather than re-emergence from endemic sources.
Pierre Nouvellet, J.V. Robotham, N.R. Naylor…·Neil M. Ferguson
The paper estimates the burden of E. coli bloodstream infections in Europe and assesses how novel diagnostics and treatments could reduce mortality and hospital stays.
Benjamin Roche, Béatrice Gaillard, Lucas Léger…·André Yébakima
This study examines the 2014 Chikungunya outbreak in Martinique, showing that human behavior, inferred from Twitter data, significantly influenced the spread of the virus.