Discover, rate, and discuss biology preprints.

The paper analyzes genomes and transcriptomes of Rhynchopus flagellates to assess endosymbiotic gene transfer (EGT) from holosporacean and chlamydiacean symbionts, finding no evidence of recent EGT and highlighting dynamic HGT patterns.

This study shows that hypoxia induces left-looping heart development in surface fish, mimicking cavefish traits, and reveals a mechanistic link between hypoxia and evolutionary changes in heart asymmetry.

This study shows that resource allocation trade-offs between sexual and asexual reproduction can enable direct selection for obligate or facultative sexuality, depending on fertility returns and initial allocations.

This paper maps gene drive dynamics onto Mendelian models to enable classical population genetics tools for predicting gene-drive outcomes.

The paper tracks eco-evolutionary dynamics in lung pathobiomes of children with cystic fibrosis, finding that P. aeruginosa variants reduce antagonism towards other pathogens, potentially stabilizing communities.

The paper quantifies gene-environment interactions in fir and beech regeneration across Europe, showing contrasting effects on germination and post-establishment survival.

The paper compares single-cell transcriptomic data from turtles, mice, and chickens to show divergence in gonadal cell types and genetic programs across sex determination systems.

This study examines how wheat domestication altered transposable element abundance and distribution, linking climate-driven genomic changes to key domestication traits.

This study uses global metagenomics to discover new plastid sequences and challenge existing models of plastid evolution in photosynthetic eukaryotes.

This study identifies conserved and diverged gene regulatory networks in mammalian cerebellum development using single-nucleus gene expression and chromatin accessibility data from six species.

The paper investigates the heritability of primary sex ratios in Lycoriella ingenua, finding evidence for heritable variation but no significant environmental effect.

This study investigates the evolutionary pathways of anaerobic mitochondrial adaptations in breviate protists by analyzing transcriptomes and predicting MRO proteomes across eight species.

This study models how partial selfing affects tandem repeat evolution under different selection pressures, finding that selfing increases homozygosity and enhances selection against TR expansions.

The paper examines elevational variation in heart mass and RV hypertrophy in Andean leaf-eared mice, finding that suppression of RV hypertrophy is linked to differential gene expression in high-altitude populations.

This study shows that sign epistasis may be absent in multi-peaked fitness landscapes when neutral mutations are included, challenging previous assumptions about reciprocal sign epistasis.

The paper assesses axillary gland toxicity and gene expression in two Corydoradinae catfish genera, finding similar toxin potency despite gene expression differences.

The paper analyzes directional heritability across trait directions and shows how matrix geometry influences evolutionary constraint using empirical G-P matrix data.

The paper examines how rising temperatures affect cryptic female choice in a marine fish, finding that warmer conditions reduce female control over fertilization.

GLADE infers gene gains, losses, and duplications across species and reconstructs ancestral genomes, showing higher accuracy than existing methods in mammalian datasets.