Discover, rate, and discuss biology preprints.

The paper explains how waning immunity drives antigenic evolution in respiratory viruses through repeated emergence and replacement of immune escape variants.

This study re-evaluates SARS-CoV-2 intrahost evolution rates in immunocompromised patients using multiple methods, finding no evidence of elevated rates compared to host-to-host transmission.

The paper compares the fitness effects of chromosomal and plasmid genes in Rhizobium leguminosarum, finding that plasmids are depleted in beneficial genes, especially ancient ones, suggesting evolutionary pressure drives beneficial genes to the chromosome.

The paper provides evidence for the independent evolution of rectal complexes in the Scarabaeoidea beetle superfamily through comparative anatomical observations.

The paper investigates the identifiability of hybrid nodes in 4-node cycles of phylogenetic networks using a pseudolikelihood coalescent model and provides sampling strategies to improve detection.

This study examines functional trade-offs and covariation among skeletal regions in carnivorans to understand their ecological adaptations and landscape topology.

This study compares the population genetics of two sympatric coral species on Guam, finding differences in genetic diversity and structure linked to habitat and morphology.

This study examines sexual reproduction in the Japanese stick insect Ramulus mikado, finding that rare males lack sperm and offspring show no paternal alleles, supporting irreversible asexual reproduction.

The paper shows that recombination modifiers can influence adaptation by altering local recombination rates, even if they reduce genome-wide polygenic adaptation.

The paper examines temperature-dependent effects of cytoplasmic male sterility on fitness, growth, and metabolism in Physa acuta mitotypes, showing CMS benefits females without restorers but costs them with restorers.

The paper calculates the probability of last-one-out gene distributions under a Markovian loss model and shows gene loss can explain observed patterns resembling horizontal gene transfer.

The paper identifies genetic polymorphism and natural selection in PvpuCSP of Plasmodium vivax, highlighting its role in adaptation and diversity.

This paper shows that horizontal gene transfer methods can detect ghost lineages in phylogenies, revealing hidden diversity despite lack of genomic data.

The paper examines how mutation rates affect viral adaptation and lethal mutagenesis, finding that high mutation rates can hinder adaptation but may enable lethal mutagenesis.

The paper develops a probabilistic model to correct biases in low-pass genome sequencing data, improving population genetic inferences.

The paper analyzes intra-host genetic diversity in SARS-CoV-2 chronic infections, finding low frequency mutations and varying divergence rates among patients.

This study examines how socio-ecological factors influence sexual selection and mating strategies in Drosophila prolongata, showing context-dependent shifts in competition modes and trait significance.

The paper shows that within-host competition between pathogens and microbiota drives molecular evolution and microbiota dysbiosis in C. elegans hosts.

This study shows that Proterozoic tectonic events, not glycan specialization, drove Flavobacterial diversification by enabling marine-to-non-marine habitat transitions.

This study presents a comprehensive phylogenomic analysis of Magnoliidae, updating its classification by resolving previously ambiguous relationships and recognizing 21 families.