Barry Denholm

The paper provides evidence for the independent evolution of rectal complexes in the Scarabaeoidea beetle superfamily through comparative anatomical observations.

The paper identifies transcription factors regulating the development of a unique beetle renal cell type involved in water conservation.

The paper identifies NHA1 as a critical cation/proton antiporter in the rectal complex of Tribolium castaneum, essential for water conservation through ion transport and developmental regulation.

The paper identifies a two-step mechanism for establishing the distal identity in Drosophila Malpighian tubules involving early Wingless/Wnt signaling and subsequent cell proliferation.