Rustom Antia

The paper shows that density-dependent population regulation can lead to greater population suppression during the endemic phase than during the initial epidemic.

This study quantifies how pre-existing tissue-resident CD8 T cells reduce donor infectiousness in a mouse model of respiratory virus transmission.

This paper develops a mechanistic model showing that intermediate antibody levels and low CD8+ T-cell immunity increase dengue disease severity, and that CD8+ T-cell responses can mitigate antibody-dependent enhancement.

The paper models factors influencing mpox's evolutionary emergence and finds that increased human-to-human transmissibility has a greater impact on its spread than zoonotic spillovers.

The paper uses epidemiological models to show that maternal antibodies and density-dependent regulation influence long-term host population suppression by novel pathogens, with outcomes sensitive to factors like R0 and virulence.

The paper explains how waning immunity drives antigenic evolution in respiratory viruses through repeated emergence and replacement of immune escape variants.

The paper uses mathematical models combined with experimental data to study how inoculum dose affects immune protection and morbidity, finding that an intermediate dose often balances these outcomes best.