Cancer BiologybioRxiv
RB1 loss triggers dependence on ESRRG in retinoblastoma
M. G. Field, J. N. Kuznetsoff, M. Zhang…·J. W. Harbour
This study identifies ESRRG as a novel dependency in retinoblastoma cells following RB1 loss, showing its role in retinogenesis and oxygen metabolism and suggesting it as a therapeutic target.
DOI 10.1126/sciadv.abm8466