Author

A J Sanchez-Jauregui Martinez

University of California, Merced

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Aqza E. John· 1 shared Cindy KlausiD· 1 shared Ferran FeixasiD· 1 shared Marc Garcia‐BorràsiD· 1 shared Michael C. ThompsoniD· 1 shared Niayesh ZarifiiD· 1 shared Roberto A. ChicaiD· 1 shared Serena E. HuntiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Aqza E. John

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1 paper

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedAug 13, 2025

Distal mutations in a designed retro-aldolase alter loop dynamics to shift and accelerate the rate-limiting step

Serena E. Hunt, Cindy Klaus, Aqza E. John…·Roberto A. Chica

The paper investigates how distal mutations in a retro-aldolase affect loop dynamics and catalytic efficiency, showing an epistatic effect when combined with active-site mutations.

10 citations

protein structuremechanistic / dynamical model

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