Marc Garcia‐Borràs

Distal mutations in a designed retro-aldolase alter loop dynamics to shift and accelerate the rate-limiting step

The paper investigates how distal mutations in a retro-aldolase affect loop dynamics and catalytic efficiency, showing an epistatic effect when combined with active-site mutations.

A computationally designed panel of diverse and selective peroxygenases for terpene oxyfunctionalization

The paper designs a panel of selective peroxygenases for terpene oxyfunctionalization using computational methods, resulting in improved enzymatic functions and new products.