Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma
Julien Paul Gigan, Paulina A García-González, Angelo Pilotti, Lou Galliot, A Reynaud, Yoan Ghaffar, Felipe Flores‐Santibáñez, Sara Ghafoori, Eve Seillier, Rosario Lavignolle, Daniela Barros, Caroline Bret, Sharon Fichaux, Alexis J. Combes, Alessandro Bani, , Rafael José Argüello
SNUPR enables single-cell UPR profiling and reveals the role of IRE-1 axis in predicting bortezomib resistance in multiple myeloma.
EMBO Molecular Medicine · Jun 29, 2026Peer-reviewedCancer Biology