Author

Evelina Gatti

Centre National de la Recherche ScientifiqueORCID 0000-0002-0667-0799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Béatrice NaliD· 3 shared Daniela BarrosiD· 3 shared Philippe PierreiD· 3 shared Rafael José ArgüelloiD· 3 shared Andreia V. MendesiD· 2 shared Angelo PilottiiD· 2 shared Beatriz H. FerreiraiD· 2 shared Bing SuiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Béatrice NalORCID

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3 papers

Recent·Most cited

Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma

Julien Paul Gigan, Paulina A García-González, Angelo Pilotti, Lou Galliot, A Reynaud, Yoan Ghaffar, Felipe Flores‐Santibáñez, Sara Ghafoori, Eve Seillier, Rosario Lavignolle, Daniela Barros, Caroline Bret, Sharon Fichaux, Alexis J. Combes, Alessandro Bani, , Rafael José Argüello

SNUPR enables single-cell UPR profiling and reveals the role of IRE-1 axis in predicting bortezomib resistance in multiple myeloma.

EMBO Molecular Medicine · Jun 29, 2026Peer-reviewedCancer Biology

VPS34-IN1 inhibits cap-mediated translation and synergizes with STING to drive type-I IFN expression in human plasmacytoid DCs

Paulo Antas, Mariana D. Machado, Fátima Leite-Pinheiro, Daniela Barros, Carlota Ramalhinho, Andreia V. Mendes, Beatriz H. Ferreira, Daniela Claudino Carvoeiro, Luís F. Mendes, Marisa Reverendo, Iola F. Duarte, Miwako Narita, Bing Su, Rafael José Argüello, Béatrice Nal, , Evelina Gatti

VPS34-IN1 inhibits cap-mediated translation and enhances STING-driven type-I IFN expression in human plasmacytoid DCs by altering SGK3 recruitment and STING degradation.

Cellular & Molecular Biology Letters · Jan 24, 2026Peer-reviewedImmunology

Induction of the ISR by AB5 subtilase cytotoxin drives IFN-I expression in pDCs via STING activation

Daniela Barros, Beatriz H. Ferreira, Paulina A García-González, Francesco Carbone, Marine Luka, Fátima Leite-Pinheiro, Mariana D. Machado, Theopisti Nikolaou, Angelo Pilotti, Emily Goguet, Paulo Antas, Andreia V. Mendes, Lichen Zhang, Marina Cresci, Lou Galliot, , Philippe Pierre

The paper shows SubAB induces IFN-I in pDCs via STING activation and UPR, highlighting a novel mechanism of immune regulation.

Proceedings of the National Academy of Sciences · May 19, 2025Peer-reviewedImmunology