Author

A. A. Guseinov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

I. Tikhonova· 2 shared A. R. B. Thomsen· 1 shared A. Wright· 1 shared B. Plouffe· 1 shared C. Daly· 1 shared C. Zhang· 1 shared G. Milligan· 1 shared H. Hahn· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

I. Tikhonova

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2 papers

Recent·Most cited

Structural basis for the ligand recognition and signaling of free fatty acid receptors

X. Zhang, A. A. Guseinov, L. Jenkins, K. Li, I. Tikhonova, G. Milligan, C. Zhang

The paper determines the structures of FFA1 and FFA4 bound to fatty acids and elucidates their activation mechanisms through cryo-EM and computational methods.

bioRxiv · Aug 20, 2023Pharmacology & Toxicology

β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

C. Daly, A. A. Guseinov, H. Hahn, A. Wright, I. Tikhonova, A. R. B. Thomsen, B. Plouffe

This study shows the vasopressin type 2 receptor can activate G proteins at endosomes both with and without beta-arrestin, challenging existing models of GPCR signaling.

bioRxiv · Apr 1, 2023Cell Biology