BiophysicsbioRxiv
Chromosome organization by one-sided and two-sided loop extrusion
E. J. Banigan, A. A. van den Berg, H. B. Brandao…·L. A. Mirny
This study investigates one-sided and two-sided loop extrusion by SMC complexes, showing that one-sided extrusion cannot recapitulate in vivo observations but variants can, suggesting SMC complexes may function as two-sided motors or have biased loading.
DOI 10.7554/elife.53558