Targeting A-Kinase Anchoring Protein 12 Phosphorylation in Hepatic Stellate Cells Regulates Liver Injury and Fibrosis in Mouse Models
K. Ramani, N. Mavila, A. Abeynayake, M. L. Tomasi, J. Wang, M. Matsuda, E. Seki
This study shows that targeting AKAP12 phosphorylation in HSCs reduces liver fibrosis by inhibiting collagen maturation and HSC activation in mouse models.
bioRxiv · Mar 15, 2022 · PreprintCell Biology