Host adaptation and convergent evolution increases antibiotic resistance without loss of virulence in a major human pathogen
A. Fajardo-Lubian, N. L. Ben Zakour, A. Agyekum, J. R. Iredell
The paper shows that antibiotic resistance in Klebsiella pneumoniae can increase without loss of virulence through changes in porin proteins, highlighting evolutionary adaptation to human hosts and antibiotic pressure.
bioRxiv · Jul 17, 2018Microbiology