Bioreversible anionic cloaking enables intracellular protein delivery with ionizable lipid nanoparticles
A. Alamgir, S. Ghosal, M. DeLisa, C. A. Alabi
This study develops a method to deliver proteins into cells using ionizable lipid nanoparticles by modifying protein surfaces with an anionic cloak, demonstrating efficacy in cancer cell killing and signaling inhibition.
ACS Central Science · May 14, 2024Peer-reviewedBioengineering