Author

A. Alarcon de la Lastra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. L. Knolhoff· 2 shared C. Zuo· 2 shared D. G. DeNardo· 2 shared J. M. Baer· 2 shared L. Ding· 2 shared R. C. Fields· 2 shared A. James· 1 shared C. Fu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

B. L. Knolhoff

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 9, 2022

Pancreas resident macrophage-induced fibrosis has divergent roles in pancreas inflammatory injury and PDAC

J. M. Baer, C. Zuo, L.-I. Kang…·D. G. DeNardo

This study shows that pancreas resident macrophages (TRMs) have distinct roles in pancreatitis and pancreatic cancer, promoting fibrosis in inflammation but driving cancer progression.

DOI 10.1101/2022.02.09.479745

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 8, 2021

Macrophage proliferation machinery leads to PDAC progression, but susceptibility to innate immunotherapy.

D. G. DeNardo, C. Zuo, J. M. Baer…·J. D. Weber

This study shows that TAM proliferation in PDAC is driven by CSF1 from fibroblasts, leading to immunosuppression and tumor progression, but also increasing sensitivity to CD40 agonist therapy.

DOI 10.1101/2021.11.08.467770

humanmouse

𝕏 PostBluesky