Author

A. Alavizargar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:mechanistic / dynamical model· 2 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Heuer· 5 shared F. Keller· 2 shared A. Elting· 1 shared B. U. Klink· 1 shared C. Gatsogiannis· 1 shared K. K. Subramaniam· 1 shared M. Chen· 1 shared M. Gass· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersBiophysics

A. Heuer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular mechanism of α-latrotoxin action

B. U. Klink, A. Alavizargar, K. K. Subramaniam, M. Chen, A. Heuer, C. Gatsogiannis

This paper reveals the molecular mechanism of α-latrotoxin action by determining its high-resolution structures and showing conformational changes during pore formation.

bioRxiv · Mar 6, 2024 · PreprintBiochemistry

Elucidating the Membrane Binding Process of a Disordered Protein: Dynamic Interplay of Anionic Lipids and the Polybasic Region

A. Alavizargar, M. Gass, M. P. Krahn, A. Heuer

This study uses MD simulations and cell culture experiments to show that LKB1's polybasic motif binds anionic lipids dynamically, with key residues and thermodynamic insights provided by a statistical model.

bioRxiv · Aug 2, 2023Biophysics

Impact of bilayer composition on the dimerization properties of the Slg1 stress sensor TMD from a multiscale analysis

F. Keller, A. Alavizargar, R. Wedlich-Soeldner, A. Heuer

This study evaluates how bilayer composition affects TMD dimerization using multiscale simulations, finding that ergosterol and phospholipid composition influence TMD-TMD and TMD-lipid interactions.

bioRxiv · Jul 27, 2022Biophysics

Effect of Cholesterol vs. Ergosterol on DPPC Bilayer Properties: Insights from Atomistic Simulations

A. Alavizargar, F. Keller, R. Wedlich-Soldner, A. Heuer

This study compares the effects of cholesterol and ergosterol on DPPC bilayer properties using molecular dynamics simulations, finding cholesterol has a stronger impact due to its planarity and molecular interactions.

The Journal of Physical Chemistry B · Jul 22, 2021Peer-reviewedBiophysics

Lipid-mediated Association of the Slg1 Transmembrane Domains in Yeast Plasma Membranes

A. Alavizargar, A. Elting, R. Wedlich Soeldner, A. Heuer

This study investigates how lipid composition influences transmembrane domain (TMD) dimerization in yeast plasma membranes using simulations and live-cell microscopy.

bioRxiv · Jun 29, 2021Biophysics