Author

A. Arnaoutov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Dasso· 5 shared V. Aksenova· 4 shared H. Park· 3 shared Y. Azuma· 3 shared N. Pandey· 2 shared S. Chen· 2 shared A. Harel· 1 shared A. Smith· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersCell Biology

M. Dasso

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5 papers

Recent·Most cited

Role of the Topoisomerase IIα Chromatin Tether domain in Nucleosome Binding & Chromosome Segregation

S. Sundararajan, H. Park, S. Kawano, M. Johansson, T. Saito-Fujita, N. Saitoh, A. Arnaoutov, M. Dasso, D. Clarke, Y. Azuma

This study shows that TopoII's Chromatin Tether domain binds methylated histone H3K27me3 to prevent anaphase ultra-fine bridges, ensuring proper chromosome segregation.

bioRxiv · Oct 3, 2021 · PreprintCell Biology

The Nuclear Pore Complex consists of two independent scaffolds

S. G. Regmi, H. Lee, R. Kaufhold, B. Fichtman, S. Chen, V. Aksenova, E. Turcotte, A. Harel, A. Arnaoutov, M. Dasso

The paper investigates the structural roles of nucleoporins in the Nuclear Pore Complex (NPC) by degrading individual components and observing the effects on NPC domains.

bioRxiv · Nov 13, 2020 · PreprintCell Biology

PICH function is required for organization of SUMOylated proteins on mitotic chromosomes

V. A. Hassebroek, H. Park, N. Pandey, B. Lerbakken, V. Aksenova, A. Arnaoutov, M. Dasso, Y. Azuma

This study shows PICH is required for organizing SUMOylated proteins on mitotic chromosomes, ensuring proper chromosome segregation through its DNA translocase activity and SUMO-binding ability.

bioRxiv · Feb 6, 2020 · PreprintCell Biology

PICH promotes SUMOylated TopoisomeraseIIα dissociation from mitotic centromeres for proper chromosome segregation

V. Hassebroek, H. Park, N. Pandey, B. T. Lerbakken, V. Aksenova, A. Arnaoutov, M. Dasso, Y. Azuma

This study shows PICH promotes dissociation of SUMOylated TopoII from mitotic chromosomes, ensuring proper chromosome segregation.

bioRxiv · Sep 24, 2019 · PreprintCell Biology

Distinct Basket Nucleoporins roles in Nuclear Pore Function and Gene Expression: Tpr is an integral component of the TREX-2 mRNA export pathway

V. Aksenova, H. N. Lee, A. Smith, S. Chen, P. Bhat, J. Iben, C. Echeverria, B. Fontoura, A. Arnaoutov, M. Dasso

bioRxiv · Jun 28, 2019Cell Biology