Author

A. Baez-Ortega

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 3 Research Focus:chromatin & epigenetic regulation· 2 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Gori· 2 shared A. Diaz-Lagares· 1 shared A. L. Bruzos· 1 shared A. Oitaben· 1 shared A. Ono· 1 shared A. P. Butler· 1 shared A. Pequeno· 1 shared A. Rodriguez-Casanova· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

K. Gori

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Author profile →

3 papers

Recent·Most cited

The evolution of two transmissible cancers in Tasmanian devils

M. R. Stammnitz, K. Gori, Y. M. Kwon, E. Harry, F. J. Martin, K. Billis, Y. Cheng, A. Baez-Ortega, W. Chow, S. Comte, H. Eggertsson, S. Fox, R. Hamede, M. E. Jones, B. Lazenby, , E. P. Murchison

This study analyzes the genetic diversity and evolution of two transmissible cancers in Tasmanian devils, revealing their emergence dates, mutation rates, and evolutionary patterns.

bioRxiv · May 27, 2022Cancer Biology

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

E. G. Alvarez, J. Demeulemeester, C. Jolly, D. Garcia-Souto, P. Otero, A. Pequeno, J. Zamora, M. Tojo, J. Temes, A. Baez-Ortega, B. Rodriguez-Martin, Y. Li, A. Oitaben, A. L. Bruzos, M. Martinez-Fernandez, , J. Tubio

The paper identifies a mutational mechanism in hepatocellular carcinoma driven by Hepatitis B virus DNA integration, leading to genomic restructuring and oncogenic rearrangements.

bioRxiv · Apr 19, 2021Cancer Biology

sigfit: flexible Bayesian inference of mutational signatures

K. Gori, A. Baez-Ortega

sigfit is an R package that uses Bayesian inference for mutational signature analysis, offering improved performance and flexibility compared to existing methods.

bioRxiv · Jan 17, 2020 · PreprintCancer Biology