Cyclic Microchip Assay for Measurement of Hundreds of Functional Proteins in Single Neurons
L. Yang, A. Ball, J. Liu, T. Jain, Y. Li, J. Wang
The paper introduces a single-cell cyclic multiplex in situ tagging (CycMIST) technology to comprehensively profile functional proteins in single neurons, demonstrating its ability to detect 182 proteins in a neuron cell line and reveal differential expression in an Alzheimer's disease model.
bioRxiv · Jun 6, 2021Bioengineering