Signals of polygenic adaptation on height have been overestimated due to uncorrected population structure in genome-wide association studies
M. Sohail, R. M. Maier, A. Ganna, A. Bloemendal, A. R. Martin, M. C. Turchin, C. W. K. Chiang, J. N. Hirschhorn, M. J. Daly, N. Patterson, B. M. Neale, I. Mathieson, D. Reich, S. R. Sunyaev
The paper shows that polygenic adaptation signals for height are overestimated due to uncorrected population structure in GWAS data.
bioRxiv · Jul 9, 2018Evolutionary Biology