The glycoprotease CpaA secreted by medically relevant Acinetobacter species targets multiple O-linked host glycoproteins
M. F. Haurat, N. E. Scott, G. Di Venanzio, J. Lopez, B. Pluvinage, A. Boraston, M. J. Ferracane, M. F. Feldman
This paper identifies CpaA, a glycoprotease from Acinetobacter species, as a broad-spectrum enzyme that cleaves multiple O-linked human glycoproteins, including those involved in complement activation, and proposes its use in glycoproteomics.
mBio · Oct 27, 2020Peer-reviewedMicrobiology