Author

A. Buganza Tepole

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 4 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. K. Rausch· 2 shared M. Mofrad· 2 shared W. D. Meador· 2 shared A. Barroso· 1 shared A. Montes· 1 shared A. R. Montes· 1 shared C. Mendenhall· 1 shared C. S. Fisher· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBioengineering

M. K. Rausch

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Integrin Mechanosensing relies on Pivot-clip Mechanism to Reinforce Cell Adhesion

A. Montes, A. Barroso, W. Wang, G. O'Connell, A. Buganza Tepole, M. Mofrad

This paper identifies a pivot-clip mechanism that enhances 5β1 integrin-fibronectin binding dynamics, reinforcing cell adhesion through conformational changes induced by mechanical forces.

bioRxiv · Dec 13, 2023Biophysics

Computational Mechanobiology Model Evaluating Healing of Postoperative Cavities Following Breast-Conserving Surgery

Z. J. Harbin, D. O. Sohutskay, E. Vanderlaan, M. A. Fontaine, C. Mendenhall, C. S. Fisher, S. L. Voytik-Harbin, A. Buganza Tepole

The paper develops a computational mechanobiological model to predict breast healing and deformation after breast-conserving surgery, showing alignment with clinical data and patient variability effects.

Computers in Biology and Medicine · Oct 1, 2023Peer-reviewedBioengineering

Multiscale Computational Framework to Investigate Integrin Mechanosensing and Cell Adhesion

A. R. Montes, G. Gutierrez, A. Buganza Tepole, M. Mofrad

This study presents a multiscale computational framework to investigate integrin mechanosensing and cell adhesion by combining molecular dynamics and finite element methods.

bioRxiv · Mar 24, 2023Biophysics

Automated model discovery for skin:Discovering the best model, data, and experiment

K. Linka, A. Buganza Tepole, G. A. Holzapfel, E. Kuhl

This paper introduces Constitutive Artificial Neural Networks (CANN) to automatically discover the best constitutive model, parameters, and experiments for skin mechanics.

bioRxiv · Dec 19, 2022Bioengineering

The biaxial mechanics of thermally denaturing skin - Part I: Experiments

W. D. Meador, G. P. P. Sugerman, A. Buganza Tepole, M. K. Rausch

This study experimentally investigates the thermo-mechanical behavior of skin under heat, revealing anisotropic shrinkage and force generation during collagen denaturation.

bioRxiv · Jun 4, 2021Bioengineering

The biaxial mechanics of thermally denaturing skin - Part II: Modeling

M. K. Rausch, W. D. Meador, J. Toaquiza Tubon, O. Moreno Flores, A. Buganza Tepole

This paper tests two models of skin thermo-mechanics to explain how skin responds to superphysiological temperatures by linking collagen denaturation to mechanical behavior.

bioRxiv · Jun 4, 2021Biophysics

Changes in the three-dimensional microscale topography of human skin with aging impact its mechanical and tribological behavior

J. G. Diosa, R. Moreno, E. L. Chica, J. A. Villarraga, A. Buganza Tepole

This study models how aging-induced changes in human skin's 3D microtopography affect its mechanical and tribological response under indentation and sliding.

bioRxiv · Oct 18, 2020Biophysics