G. Gutierrez

Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy

This study shows that interrupting CD8:Treg crosstalk during PD-1 immunotherapy improves melanoma control by reducing Treg accumulation.

Multiscale Computational Framework to Investigate Integrin Mechanosensing and Cell Adhesion

This study presents a multiscale computational framework to investigate integrin mechanosensing and cell adhesion by combining molecular dynamics and finite element methods.

Polygenic variation in sexual investment across an ephemerality gradient in Daphnia pulex

The paper investigates polygenic variation in sexual investment in Daphnia pulex across an ephemerality gradient, finding that clonal diversity, not genetic diversity, varies with ephemerality and identifying multiple QTL for male production.

Mobilization of a Kluyvera-like arnBCADTEF operon, besides mcr genes, confers colistin resistance to Escherichia coli isolated from healthy animals

This study identifies mobilization of a Kluyvera-like arnBCADTEF operon as a new colistin resistance mechanism in E. coli from healthy animals, alongside mcr genes and chromosomal mutations.

Integrated single-cell transcriptomics and chromatin accessibility analysis reveals novel regulators of mammary epithelial cell identity

The paper integrates single-cell transcriptomics and chromatin accessibility analysis to identify novel regulatory elements in mouse mammary epithelial cells and their differentiation states.