Author

R. Moreno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

A. T. Dinkova-Kostova· 2 shared L. de la Vega· 2 shared A. Buganza Tepole· 1 shared A. E. Kiib· 1 shared A. W. Jackson· 1 shared B. J. Currie· 1 shared B. Prasad· 1 shared C. Guzman-Cardozo· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

A. T. Dinkova-Kostova

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, are potent BACH1 inhibitors

L. Casares, R. Moreno, M. Higgins, S. D. Naidu, G. Neill, L. Cassin, A. E. Kiib, E. B. Svenningsen, T. Honda, T. B. Poulsen, A. T. Dinkova-Kostova, D. Olagnier, L. de la Vega

This study identifies CDDO-derivatives as BACH1 inhibitors, explaining their higher potency as HMOX1 inducers compared to CDDO.

bioRxiv · Oct 29, 2021 · PreprintCell Biology

The human neuronal receptor NgR1 bridges reovirus capsid proteins to initiate infection

D. M. Sutherland, M. Strebl, M. Koehler, O. L. Welsh, X. Yu, L. Hu, R. dos Santos Natividade, J. J. Knowlton, G. M. Taylor, R. Moreno, P. Woerz, Z. L. Lonergan, P. Aravamudhan, C. Guzman-Cardozo, D. Alsteens, , T. S. Dermody

This study identifies how NgR1 bridges reovirus capsid proteins to initiate infection, revealing a unique binding interface and its role in virus entry and receptor ligand interactions.

bioRxiv · Jul 23, 2021 · PreprintMicrobiology

Changes in the three-dimensional microscale topography of human skin with aging impact its mechanical and tribological behavior

J. G. Diosa, R. Moreno, E. L. Chica, J. A. Villarraga, A. Buganza Tepole

This study models how aging-induced changes in human skin's 3D microtopography affect its mechanical and tribological response under indentation and sliding.

bioRxiv · Oct 18, 2020Biophysics

DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress in triple-negative breast cancer

R. Moreno, S. Banerjee, A. W. Jackson, J. Quinn, G. Baillie, J. E. Dixon, A. T. Dinkova-Kostova, J. Edwards, L. de la Vega

This study identifies DYRK2 as a kinase that phosphorylates HSF1, enhancing its activity and promoting resistance to proteotoxic stress in TNBC, with implications for therapeutic targeting.

bioRxiv · Jun 2, 2019Cancer Biology

A Mouse Model Of Binge Alcohol Consumption and Burkholderia Infection

V. Jimenez, R. Moreno, E. Settles, B. J. Currie, P. Keim, F. Monroy

This study shows that binge alcohol consumption increases Burkholderia infection severity by reducing immune function and increasing tissue permeability and bacterial spread.

bioRxiv · Jul 30, 2018Immunology