UNC-45 assisted myosin folding depends on a conserved FX3HY motif implicated in Freeman Sheldon Syndrome
A. Vogel, R. Arnese, R. Gudino Carrillo, D. Sehr, A. Bylicki, A. Meinhart, T. Clausen
This study identifies the FX3HY motif as essential for UNC-45-mediated myosin folding, linking its disruption to Freeman Sheldon Syndrome and myopathies.
bioRxiv · Aug 8, 2022Biochemistry