A Single Cell Cloning Platform for Gene Edited Functional Murine Hematopoietic Stem Cells
H. J. Becker, R. Ishida, A. C. Wilkinson, T. Kimura, M. S. J. Lee, C. Coban, Y. Ota, A. Tojo, D. Kent, S. Yamazaki
The paper presents a method to expand and profile genetically edited murine hematopoietic stem cells at clonal density to reduce genetic heterogeneity before transplantation.
bioRxiv · Mar 23, 2022 · PreprintCell Biology