A highly efficient reporter system for identifying and characterizing in vitro expanded hematopoietic stem cells
J. L. C. Che, D. Bode, I. Kucinski, A. H. Cull, F. Bain, M. Barile, G. Boyd, M. Belmonte, M. Jassinskaja, J. Rubio-Lara, M. S. Shepherd, A. Clay, A. C. Wilkinson, H. Nakauchi, S. Yamazaki, , D. G. Kent
This paper introduces a reporter system to identify and characterize expanded hematopoietic stem cells, showing their molecular profile resembles fetal liver HSCs and shares gene expression signatures with functional HSCs from various sources.
bioRxiv · Jun 18, 2021 · PreprintCell Biology