A. Cartier

Engineered high-density lipoprotein particles that chaperone bioactive lipid mediators to combat endothelial dysfunction and thromboinflammation

This paper constructs engineered HDL-like particles that chaperone bioactive lipids to reduce inflammation and endothelial dysfunction.

Multicenter reverse-phase protein array data integration

This paper integrates multicenter reverse-phase protein array data from breast cancer cell responses to two drugs, quantifying 86,832 spots across three platforms to create a public resource for comparing RPPA workflows.

Proliferation genes repressed by TGF-β are downstream of Slug/Snail2 in normal bronchial epithelial progenitors and are deregulated in COPD

The paper investigates Slug/Snail2 downstream genes in bronchial epithelial progenitors, showing differences in proliferation gene repression between normal and COPD cells.

Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies

The paper assesses variability between RPPA platforms and identifies consistent protein expression and phosphorylation signatures across different platforms and workflows.

Endothelial sphingosine 1-phosphate receptors promote vascular normalization to influence tumor growth and metastasis

This study shows that S1PR1 in tumor vessels promotes vascular normalization, reducing tumor growth and metastasis, and enhances the effectiveness of chemotherapy.

Heterotypic inter-GPCR β-arrestin coupling regulates lymphatic endothelial junctional architecture in murine lymph nodes

The paper identifies LPAR1-induced S1PR1/β-arrestin coupling as a mechanism regulating lymphatic endothelial junctional architecture in murine lymph nodes.