Engraftment, fate, and function of HoxB8-conditional neutrophil progenitors in the unconditioned murine host
J. T. Cohen, M. Danise, K. D. Hinman, B. M. Neumann, R. Johnson, Z. S. Wilson, A. Chorzalska, P. M. Dubielecka, C. T. Lefort
This study shows HoxB8-conditional neutrophil progenitors can engraft in naive mice without niche conditioning, generate mature neutrophils, and respond to inflammation via known recruitment mechanisms.
bioRxiv · Dec 20, 2021Immunology