Author

A. D. Kelleher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Brilot· 2 shared M. Singh· 2 shared A. Aggarwal· 1 shared A. Akerman· 1 shared A. Carr· 1 shared A. Howard-Jones· 1 shared A. Khromykh· 1 shared A. Kindinger· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

F. Brilot

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

C. Young, M. Singh, K. J. Jackson, M. A. Field, T. J. Peters, S. Angioletti-Uberti, D. Frenkel, S. Ravishankar, M. Gupta, J. J. Wang, D. Agapiou, M. L. Faulks, G. Al-Eryani, F. Luciani, T. P. Gordon, , C. C. Goodnow

The paper traces the evolution of autoantibodies in HCV-CV patients, revealing convergent somatic mutations and compromised solubility in pathogenic B cells.

bioRxiv · Jan 7, 2024Immunology

TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2

A. Aggarwal, C. Fichter, V. Milogiannakis, T. Ison, M. Ruiz Silva, C. Esneau, N. Bartlett, L. Burrell, S. Patel, M. Churchill, T. Angelovich, R. Parry, J. D. Sng, G. G. Neely, C. L. Moreno, , S. G. Turville

The paper shows Omicron SARS-CoV-2 lineages rely on ACE2 without TMPRSS2 complexes for entry, due to changes in the ACE2 Collectrin-Like Domain affecting TMPRSS2 activation.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Clonal dynamics of SARS-CoV-2-specific T cells in children and adults with COVID-19

W. H. Khoo, K. Jackson, C. Phetsouphanh, J. Zaunders, J. Alquicira-Hernandez, S. Yazar, S. Ruiz-Diaz, M. Singh, R. Dhenni, W. Kyaw, F. Tea, V. Merheb, F. Lee, R. Burrell, A. Howard-Jones, , T. G. Phan

This study compares T cell responses in children and adults with mild/asymptomatic COVID-19, finding differences in T cell diversity and memory formation.

bioRxiv · Jan 30, 2022Immunology