Author

T. J. Peters

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:differential expression· 4 Organism:mouse· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

J. H. Reed· 4 shared C. C. Goodnow· 3 shared D. Suan· 3 shared E. Masle-Farquhar· 3 shared M. Singh· 3 shared R. Brink· 3 shared G. Al-Eryani· 2 shared G. Uzel· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. H. Reed

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Author profile →

5 papers

Recent·Most cited

Self-reactive B cells traverse a perfect storm of somatic mutagenesis to cause a virus-induced autoimmune disease

C. Young, M. Singh, K. J. Jackson, M. A. Field, T. J. Peters, S. Angioletti-Uberti, D. Frenkel, S. Ravishankar, M. Gupta, J. J. Wang, D. Agapiou, M. L. Faulks, G. Al-Eryani, F. Luciani, T. P. Gordon, , C. C. Goodnow

The paper traces the evolution of autoantibodies in HCV-CV patients, revealing convergent somatic mutations and compromised solubility in pathogenic B cells.

bioRxiv · Jan 7, 2024Immunology

STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2Dhi CD8 killer T cells

E. Masle-Farquhar, K. J. L. Jackson, T. J. Peters, G. Al-Eryani, M. Singh, K. J. Payne, G. Rao, G. Apps, J. Kingham, C. J. Jara, K. Skvortsova, A. Swarbrick, C. Ma, D. Suan, G. Uzel, , C. C. Goodnow

This study shows that STAT3 gain-of-function mutations in leukemia drive autoimmune pathology by causing NKG2Dhi CD8 T cell oligoclonal expansion and cytotoxic activity.

bioRxiv · Feb 11, 2022 · PreprintImmunology

Overactive STAT3 drives accumulation of disease-associated CD21low B cells

E. Masle-Farquhar, T. J. Peters, K. J. Jackson, M. Singh, C. S. Ma, D. Suan, G. Uzel, I. Chua, J. W. Leiding, K. Heiskanen, K. Preece, L. Kainulainen, M. O Sullivan, M. A. Cooper, M. R. Seppänen, , C. C. Goodnow

This study shows that overactive STAT3 leads to the accumulation of disease-associated CD21low B cells in both humans and mice.

bioRxiv · Dec 20, 2021 · PreprintImmunology

Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint

E. Masle-Farquhar, T. J. Peters, L. A. Miosge, I. A. Parish, C. Weigel, C. C. Oakes, J. H. Reed, C. Goodnow

This study identifies EGR2 and EGR3 as critical transcription factors that suppress CD21low and B1 B cell accumulation by repressing plasma cell differentiation and follicular germinal center formation.

bioRxiv · Jul 1, 2021Immunology

A novel microRNA-based strategy to expand the differentiation potency of stem cells

M. Salazar-Roa, M. Trakala, M. Alvarez-Fernandez, F. Valdes-Mora, C. Zhong, J. Munoz, Y. Yu, T. J. Peters, O. Grana Castro, R. Serrano, E. Zapatero-Solana, M. Abad, M. J. Bueno, M. Gomez de Cedron, J. Fernandez-Piqueras, , M. Malumbres

This study shows that transient exposure to miR-203 enhances the differentiation capacity of murine and human PSCs by reversing DNA methylation.

bioRxiv · Nov 4, 2019Cell Biology