A structural basis for inhibition of the complement initiator protease C1r by Lyme disease spirochetes
R. J. Garrigues, A. D. P. Pierce, M. Hammel, J. T. Skare, B. L. Garcia
This study identifies the structural mechanism by which BBK32 inhibits the classical complement pathway by binding and inactivating C1r.
bioRxiv · Jan 21, 2021Microbiology