Author

A. d. S. Santiago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

R. M. Counago· 2 shared B. J. Eduful· 1 shared C. G. Langendorf· 1 shared C. I. Wells· 1 shared D. H. Drewry· 1 shared J. Elkins· 1 shared J. R. Pilotte· 1 shared J. S. Oakhill· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

R. M. Counago

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2 papers

Recent·Most cited

Cancer BiologybioRxivJan 8, 2020

In depth analysis of kinase cross screening data to identify CAMKK2 inhibitory scaffolds

S. O'Byrne, J. W. Scott, J. R. Pilotte…·D. H. Drewry

This paper reviews CAMKK2's role in biology and disease, identifies starting points for inhibitor development using literature and databases, and highlights potential for selective inhibitors in oncology, metabolism, and inflammation.

DOI 10.3390/molecules25020325

experimental assay

𝕏 PostBluesky

BiochemistrybioRxivMar 31, 2018

Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors

A. d. S. Santiago, R. M. Counago, P. Zonzini Ramos…·J. Elkins

The paper determines the crystal structure of CAMKK1 with inhibitors and identifies structural differences from CAMKK2 to guide the design of specific inhibitors.

DOI 10.1038/s41598-018-33043-4

protein structureexperimental assay

𝕏 PostBluesky