Author

A. D. St-Jacques

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. M. Damry· 1 shared J. M. Rodriguez· 1 shared M. C. Thompson· 1 shared M. G. Eason· 1 shared N. K. Goto· 1 shared R. A. Chica· 1 shared S. M. Foster· 1 shared S. T. Khan· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. M. Damry

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1 paper

Recent·Most cited

Computational remodeling of an enzyme conformational landscape for altered substrate selectivity

A. D. St-Jacques, J. M. Rodriguez, M. G. Eason, S. M. Foster, S. T. Khan, A. M. Damry, N. K. Goto, M. C. Thompson, R. A. Chica

This study computationally redesigns an enzyme's conformational landscape to enhance catalytic efficiency with a non-native substrate, achieving up to 1900-fold selectivity switch.

bioRxiv · Sep 16, 2022Biophysics