Author

J. M. Rodriguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Approach:deep learning· 2 Assay:protein structure· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. C. Thompson· 2 shared R. A. Chica· 2 shared A. C. Hernando Insua· 1 shared A. D. St-Jacques· 1 shared A. Demaria· 1 shared A. Ferrino-Iriarte· 1 shared A. J. Auguste· 1 shared A. M. Damry· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

M. C. Thompson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

On the Role of VP3-PI3P Interaction in Birnavirus Endosomal Membrane Targeting

F. A. Zanetti, I. Fernandez, E. Baquero, P. Guardado-Calvo, A. Ferrino-Iriarte, S. Dubois, E. Morel, V. Alfonso, M. O. Aguilera, E. E. Celayes, L. M. Polo, L. Suhaiman, V. V. Galassi, M. V. Chiarpotti, C. Allende, , L. R. Delgui

This paper investigates how VP3 protein of birnaviruses targets endosomal membranes via PI3P binding, revealing a two-stage mechanism critical for viral replication.

bioRxiv · Feb 20, 2024Microbiology

Design of efficient artificial enzymes using crystallographically-enhanced conformational sampling

R. V. Rakotoharisoa, B. Seifinoferest, N. Zarifi, J. D. M. Miller, J. M. Rodriguez, M. C. Thompson, R. A. Chica

This paper designs artificial enzymes with high catalytic efficiency using crystallography-enhanced computational methods, achieving improvements comparable to directed evolution.

bioRxiv · Nov 1, 2023Biochemistry

A Gamma-adapted recombinant subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.

L. M. Coria, J. M. Rodriguez, A. Demaria, L. A. Bruno, M. Rios Medrano, C. Pueblas Castro, E. F. Castro, S. A. Del Priore, A. C. Hernando Insua, I. G. Kaufmann, L. M. Saposnik, W. B. Stone, L. Prado, V. Krum, F. M. Zurvarra, , J. Cassataro

This paper develops a Gamma-adapted subunit vaccine that induces broad neutralizing antibodies and protects mice against SARS-CoV-2 variants, including Omicron.

bioRxiv · Jan 3, 2023Immunology

Computational remodeling of an enzyme conformational landscape for altered substrate selectivity

A. D. St-Jacques, J. M. Rodriguez, M. G. Eason, S. M. Foster, S. T. Khan, A. M. Damry, N. K. Goto, M. C. Thompson, R. A. Chica

This study computationally redesigns an enzyme's conformational landscape to enhance catalytic efficiency with a non-native substrate, achieving up to 1900-fold selectivity switch.

bioRxiv · Sep 16, 2022Biophysics

Production of multiple bacteriocins, including the novel bacteriocin gassericin M, by Lactobacillus gasseri LM19, a strain isolated from human milk

E. Garcia-Gutierrez, P. M. O'Connor, I. J. Colquhoun, N. M. Vior, J. M. Rodriguez, M. J. Mayer, P. D. Cotter, A. Narbad

The paper identifies Lactobacillus gasseri LM19 as a human milk isolate producing multiple bacteriocins, including a novel one, gassericin M, and shows its potential to maintain gut homeostasis.

bioRxiv · Nov 13, 2019Microbiology