Author

S. T. Khan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. S. Nunes· 2 shared A. D. St-Jacques· 1 shared A. Dal Cin· 1 shared A. M. Damry· 1 shared A. P. McGuigan· 1 shared J. M. Rodriguez· 1 shared K. Singh· 1 shared M. C. Thompson· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

S. S. Nunes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Uncovering the transcriptomic heterogeneity of pancreatic endothelial cells using integrative and comparative single cell gene expression analysis

S. T. Khan, N. Ahuja, S. Taib, S. Vohra, O. Cleaver, S. S. Nunes

The paper identifies transcriptomic features of pancreatic endothelial cells through single-cell RNA sequencing and validates findings in independent datasets and tissue samples.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

Computational remodeling of an enzyme conformational landscape for altered substrate selectivity

A. D. St-Jacques, J. M. Rodriguez, M. G. Eason, S. M. Foster, S. T. Khan, A. M. Damry, N. K. Goto, M. C. Thompson, R. A. Chica

This study computationally redesigns an enzyme's conformational landscape to enhance catalytic efficiency with a non-native substrate, achieving up to 1900-fold selectivity switch.

bioRxiv · Sep 16, 2022Biophysics

A three-dimensional human adipocyte model of fatty acid-induced obesity

V. M. Pieters, S. T. Rjaibi, K. Singh, N. T. Li, S. T. Khan, S. S. Nunes, A. Dal Cin, P. M. Gilbert, A. P. McGuigan

This paper develops a 3D in vitro model of human adipocytes to study fatty acid-induced obesity and its associated pathologies.

bioRxiv · Feb 24, 2022Bioengineering